Sentence examples for a target based approach from inspiring English sources

However, validation of the MAPK pathway opens up the possibility of a target based approach in the future.

Moreover, the poor understanding of relevant targets in the parasite field has led to poor success rates when using a target based drug discovery approach, making a phenotypic strategy particularly attractive in this context.

As Swinney et al have shown [1], there is compelling evidence that first-in-class drugs are more likely to be found by assays that measure a clinically meaningful phenotype in a physiologically relevant system rather than a single target based screening approach in an artificial setting.

This study shows that the salt content of bread has been progressively reduced over time, contributing to the evidence base that a target-based approach to salt reduction can lead to reductions being made.

In Phatak et al. [ 2], a computational method for drug repositioning differs from previous similarity-based approaches since it combines chemical drug structures and drug target information computing similarity of drug target profiles via a bipartite-graph based approach.

We report on a target-based approach to identify possible Mycobacterium tuberculosis DXS inhibitors from the structure of a known transketolase inhibitor.

A target-based approach has the advantage of being transparent and relatively simple to aggregate across countries to reach a global target.

The logic in the use of signatures is the ability to greatly expand the number of opportunities for identifying compounds that have anti-cancer activity, recognizing the fact that a target-based approach is limited by available targets that are amenable to conventional drug screens.

Molecular docking is a target-based approach [ 4, 5], which predicts the preferred orientation by conformation searching and energy minimization.

Other countries around the world now need to follow suit and develop a target-based approach to reducing salt content of processed foods.

This research, using the example of bread, demonstrates how a target-based approach to salt reduction can lead to salt reductions being made across the board.