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Pioneering thought leader in the effort to understand from a systems viewpoint the impact of computers on human society, planet Earth, and beyond.
The lessons and tools of complexity science can help to understand and to combat the obesity epidemic, but only if complexity is taken seriously and the problem of obesity is approached from a systems viewpoint.
We argue that chemical engineering conversant with a systems viewpoint that is deeply embedded in its culture and the ability to tackle problems across a broad range of length and time scales is in excellent position to master and develop new tools and to tackle the many challenges posed by complex systems.
Interrogating C. beijerinckii metabolism from a systems viewpoint using constraint-based modeling allows for simulation of the global effect of genetic modifications.
The genome-scale model allows one to analyze the cell from a systems viewpoint to predict whole-cell effects of genetic changes, and to simulate known and hypothesized phenotypes.
Having a genome-scale model for C. beijerinckii is advantageous because it helps provide a global picture of metabolism--enabling interrogation of the interplay between the various fermentation products of the microorganism from a systems viewpoint.
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Both have the following issues: distortion and resolution of the real scene; delay of a system; viewpoint matching; engineering and cost factors.
A system viewpoint is essential in the study of wave energy converters, since several different energy domains are involved in such devices.
Full-scale aircraft structural fatigue tests are extremely complex from a control systems viewpoint.
Besides providing a distributed systems viewpoint of this new kind of computational system, our analysis also puts into perspective the fact that human computation introduces new challenges in terms of effective D&M strategies.
Table 1 Key concepts in diabetes from a systems medicine viewpoint 1. Can diabetes trajectories be considered as multidimensional objects such that associated risks and comorbidities can be more accurately accounted for? 2. Are electronic health records (EHR) innovative or even disruptive when inducing re-phenotyping and new patient stratifications?
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