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A systemic function recommendation process is elaborated, and a case study is presented to showcase practical applications.
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It should be emphasized that the cardiac effects are abolished whereas all systemic functions of ANP/GC-A are preserved in CM GC-A KO mice [ 18].
The other is a "systemic HMGB1" function mediated by HMGB1 secreted by HMGB1 producing cells to induce remote organ failure in the lungs, liver, kidneys, and other organs during hemorrhagic states.
The single investigator evaluated cardiac anatomy and left ventricular systemic function (Simpson biplane method), normal systolic function was a criterion for inclusion in the study.
This could be due to leakage after localized release rather than to specific systemic function [36], and CGRP does not affect the resting vascular tone [37].
At least half of all PG patients also suffer from illnesses that affect their systemic function.
Eventually, the systemic function will be affected, such as rhabdomyolysis and injuries of heart, liver and neural system.
Serum is one of the most easily procured patient specimens and it is perceived to contain many of the molecules that might indicate systemic function.
Leptin, an adipokine that regulates energy balance through a wide range of systemic functions, is associated with obesity and insulin resistance [ 6, 7].
For a better understanding of the systemic functions and the cooperative interactions between genes within the functional modules, FunMod checks whether the sub-network topology fits into a specific module.
Health system strengthening interventions seek to strengthen core systemic functions of the local health system.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com