Sentence examples for a systemic decrease from inspiring English sources

In order to determine if the depletion of Tregs in the adipose was a consequence of a systemic decrease in Tregs, we analyzed splenic content of Tregs.

All together these data indicate that low-level Pb contributes to a systemic decrease in skeletal mass.

These results demonstrate that whole larval injection with dsRNA results in a high and systemic decrease of both mRNA and protein in the bacteriome tissue.

Also, the appetite-suppressing and anti-weight gain effects of rimonabant are associated with systemic decrease of inflammatory response [ 234].

Moreover, if we are to learn from the two manipulations most reliably known to increase mouse lifespan, loss of GH / IGF-I signals and dietary restriction, we'd walk away the notion that, at a systemic level, decreased expression of certain HSP-encoding genes (e.g., Hsph1) is associated with longevity more so than increased HSP expression [ 28, 39].

While the positive results of a few state reforms are heartening, the data do not reflect a systemic movement to decrease unnecessary incarceration permanently.

Recently antitumor efficacy of targeted formulations has been correlated with a systemic effect: a decrease of white blood cell count.

As expected, there were no obvious differences in plasma concentrations between patients in Cohort A and Cohort B. There was no indication of a systemic increase or decrease in afatinib trough values up to 6 months of treatment with afatinib (data not shown).

The observation that blood pressure was not normalized following resuscitation to a normal blood volume suggests that the haemorrhage caused a systemic inflammatory reaction with decreased vascular resistance and/or decreased cardiac contractility [18].

There is, however, an ongoing debate, if metformin acts via a systemic effect solely by decreased insulin levels (and/or less obesity) or has direct actions on tumor cells as is observed experimentally.

Osteoporosis is a systemic skeletal disease characterized by decreased bone density and a deterioration in bone quality (microarchitectural changes), leading to compromised bone strength and an enhanced risk of fractures that are not due to significant trauma [4].