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The phrase "a systematic understanding" is correct and usable in written English.
It can be used when discussing a thorough and organized comprehension of a subject or concept.
Example: "To excel in this field, one must develop a systematic understanding of the underlying principles and theories."
Alternatives: "an organized comprehension" or "a structured grasp".
Exact(60)
The KEGG pathway database can facilitate a systematic understanding of the molecular interactions among genes, in terms of networks [ 30].
In order to get a systematic understanding of the disease or phenotypes we have to first understand what biological functions contribute to these changes, and perform a comparison between conditions using groups of genes defined by biological pathways.
As far as I know, no other culture has ever undertaken a systematic understanding of the world's various societies.
To see if readers could moderate themselves, Lampe analysed millions of Slashdot user actions and developed a systematic understanding of volunteer moderation.
Mnemonic feats were not only a practically useful party trick, but were often held to enable a practitioner to arrive at a systematic understanding of the world.
Classification is basic to all science as a preliminary step in reducing data to manageable proportions and in moving toward a systematic understanding of a subject matter.
Though useful for some purposes, geographical classifications contribute minimally to the task of providing a systematic understanding of human religions and religiousness.
No one has given them much in the way of a systematic understanding of, for example, history – and so they have only a sketchy idea of what is happening to them.
What is the level of progress towards a systematic understanding of how to use gamification in educational contexts?
This study represents a small step in a systematic understanding of how games can be used to assess behavior change.
More generally, it contributes to a systematic understanding of local-level immigrant policymaking in recent and contemporary Western Europe.
More suggestions(15)
a consistent understanding
a systematic sympathy
a systematic appreciation
a systematic mistake
a keen understanding
a systematic war
a full understanding
a silent understanding
a systematic way
a bad understanding
a systematic blood-doping
a complex understanding
a systematic literature
a systematic design
a systematic rightwinger
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com