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These findings suggest that EMT is not a static process, and that mesenchymal transition of epithelial cells is not a synchronized process in the IPF lung.
While apoptosis is a synchronized process leading to cell death, autophagy is considered both a mechanism to protect from toxicity in stress conditions as well as a mediator of cell death.
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Embryo implantation is a complex, synchronized process that requires establishment of a reciprocal dialogue between a receptive endometrium and developing blastocysts.
Because each of the fluorescent spots will eventually become mature campaniform sensilla, our data suggest that continued active division and maturation of the sensory organ occurs after the emergence of the adult and that this is a weakly synchronized process.
Apoptosis is an orderly and synchronized process, regulated by two different pathways, the intrinsic way (mitochondrial) and extrinsic one (the death receptor).
This may be due to a more complex and less synchronized process of metacyclogenesis in vivo than in vitro.
Such mechanism could operate on a single cell level, however, since any given stromal cell is likely to be in contact with several progenitor cells at a given time, this would require a synchronized differentiation process and an ability of the stromal cell to return to a ground stage when the hematopoietic cells have left to enter another developmental niche.
Comparing with other papers, here we consider the effect of internal noise, time-delay and parametric mismatch in the synchronized process.
Our present data also argue in favor of a non-synchronized process of adult wing neurogenesis after emergence and raise the question of the role of environmental cues in shaping appropriate variants.
We hope that the methods and procedures discussed herein will not only foster initiatives toward the G10K project, but also contribute to a synchronized understanding of the genetic processes heretofore not available.
Temporal organization of biological processes requires massively parallel processing on a synchronized time-base.
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