The phrase "a symptomatic setting" is correct and usable in written English.
It can be used in contexts related to medical, psychological, or social discussions where symptoms are being observed or analyzed in a particular environment.
Example: "In a symptomatic setting, the researchers noted various behavioral changes among the participants."
Alternatives: "a symptomatic environment" or "a symptomatic context".
Thus DBT has the potential of increasing work-flow efficiency in a symptomatic setting by reducing benign biopsies.
Between January 2001 and December 2008, mammograms and ultrasounds performed in a symptomatic setting were prospectively UK scored and the percentage of cancer outcomes within each group calculated.
DBT increases diagnostic sensitivity in a symptomatic setting and reduces the number of M3 mammograms, when used as an adjuvant to 2D images.
The study investigated the accuracy of two-view full-field digital (2D) mammograms (FFDM) by comparing its performance with two-view digital breast tomosynthesis (3D) plus FFDM combination in a symptomatic setting.
A single randomised study of 547 patients performed by Von Wagner et al. (manuscript recently accepted by Radiology) found that CTC was more acceptable than colonoscopy and associated with less physical side-effects, but this was performed in a symptomatic setting (data derived by personal communication).
We think this much less likely to be a significant issue in this symptomatic setting as compared with patients diagnosed in screening programmes of asymptomatic populations.
To use an example from a symptomatic clinical setting, a patient presenting with chest symptoms and an area of shadowing on a chest radiograph will wish to take an antibiotic for pneumonia, although the diagnosis is not conclusive, the disease may be of viral origin and many bacterial pneumonias resolve without treatment.
Interestingly, two recent studies confirmed a high sensitivity of CESM (94 95 %) with higher values of specificity: 81%% in the symptomatic setting [35] and 74 % in the post-screening assessment [36].
DBT helps characterise indeterminate lesions more accurately compared with FFDM in the symptomatic setting.
Ductal carcinoma in situ (DCIS) is encountered much more frequently in the screening population compared to the symptomatic setting.
Most previous published work comes from the USA, where the structure of screening programmes differs from that employed in Europe and much of the research has been conducted in the symptomatic setting.
