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An initial fast release for about 12 h was followed by a sustained released of drug from the micelles.
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The scaffold allows cell attachment, and provides mechanical support and a sustained release of neurotrophins.
Their release pattern from these drug-entrapped nanostructures showed a sustained release of drugs over a period of time.
In vitro release studies, through stomach and intestinal simulation, showed a sustained release of PAs from PLA-NPs.
In vitro release studies showed a sustained release of PIP to >75% over 12 h between pH 1.2 and 6.4.
Furthermore, a range of drug encapsulates NPs were produced and showed a sustained release of the encapsulated drug.
The composite scaffolds had well controlled and interconnected pore structures, high mechanical strength and a sustained release of DEX.
The copolymer hydrogel was confirmed as a protein depot carrier; it showed a sustained release of FITC-BSA over 6 weeks.
The in vitro release of the drug displayed a biphasic pattern with a low initial burst and a sustained release of up to 14 days.
Although all types of zein nanoparticles showed a sustained release of curcumin, cross-linking via tannic acid played an important role to make zein nanoparticles more resistant against simulated intestinal digestion.
In the present work, the unstable LD LA was entrapped into biodegradable poly(lactic-co-glycolic acid) (PLGA) microspheres designed as depot systems to protect this prodrug against degradation and to obtain a sustained release of the intact compound.
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CEO of Professional Science Editing for Scientists @ prosciediting.com