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The scaffold allows cell attachment, and provides mechanical support and a sustained release of neurotrophins.
The composite scaffolds had well controlled and interconnected pore structures, high mechanical strength and a sustained release of DEX.
Their release pattern from these drug-entrapped nanostructures showed a sustained release of drugs over a period of time.
In vitro release studies, through stomach and intestinal simulation, showed a sustained release of PAs from PLA-NPs.
In vitro release studies showed a sustained release of PIP to >75% over 12 h between pH 1.2 and 6.4.
Furthermore, a range of drug encapsulates NPs were produced and showed a sustained release of the encapsulated drug.
The copolymer hydrogel was confirmed as a protein depot carrier; it showed a sustained release of FITC-BSA over 6 weeks.
The in vitro release of the drug displayed a biphasic pattern with a low initial burst and a sustained release of up to 14 days.
Although all types of zein nanoparticles showed a sustained release of curcumin, cross-linking via tannic acid played an important role to make zein nanoparticles more resistant against simulated intestinal digestion.
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The present in vitro and in vivo study examines whether IBU-BB provide a sustained-release of the drug.
This allowed crosslinked tubes to deliver a sustained-release of NTFs over 30 days whereas noncrosslinked tubes rapidly degraded within 2 days.
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CEO of Professional Science Editing for Scientists @ prosciediting.com