Participants were asked to rate each recommendation and supporting rationale for clarity, coherence and importance, on a seven-point Likert scale, and to provide suggestions for any modifications.
We discuss the implications and supporting rationale for using participatory mapping in community meetings.
Based on our findings from Phases 1 and 2, we drafted a set of nine recommendations with supporting rationales for enhancing the integration of evidence during the prenatal record review process across Canadian jurisdictions.
This mechanism is completely different from how classical ESAs function, supporting a rationale for using sotatercept as a new therapeutic agent to manage anaemia in diseases of ineffective erythropoiesis, such as β-Thalassaemia, Diamond-Blackfan Anaemia (DBA), or MDS.
These findings therefore support a rationale for targeting the death receptor pathway, as a strategy for bypassing platinum resistance.
These results support a rationale for manipulating Treg to enhance cancer immunotherapy.
Additional findings may support a rationale for the development of further studies to test the hypothesis that the effects of leptin replacement may improve cognition in leptin-sufficient patients with delay or decline of cognitive function.
Together, these results support a rationale for screening in liquid media to uncover different and potentially novel components of iron metabolism in yeast.
Thus, these studies provided compelling evidence that the presence of Tregs are neuroprotective and support a rationale for Tregs immunotherapy in patients with ALS.
The design of our observational methods implied compromises that did not support a rationale for calculating intra-observer repeatability and inter-observer reproducibility based on correlation statistics.
These data demonstrate a role for IL-21 in the modulation of collagen-specific T-cell responses and the pathology of arthritis, supporting a rationale for blockade of the IL-21 pathway in rheumatoid arthritis.
