Last year Genentech argued that the decrease in progression-free survival in its supplementary studies was not due to the pairing of Avastin with drugs other than Taxol.
Supplementary studies were used to define a knocked-down stress strain curve, and to show that using base case results is conservative for more complex situations.
Supplementary studies are conducted in certain instances either as a follow-up to the findings from this initial testing battery and/or to satisfy a regulatory requirement.
Some analyses required extra data; therefore, two supplementary studies were conducted.
Due to obvious technical limitations, we were able to focus only on selected aspects of organ injury/dysfunction and supplementary studies are necessary to expand onto those omitted elements.
At this phase of our optical instrument validation, supplementary studies are needed to address whether this technology can be also useful for patients presenting systemic diseases like CAD, without major undesirable influence.
A supplementary study confirmed that the immune response is not instrumental for IRE ablation which broadens the potential application space for IRE treatment to immunodepressed patients [38].
Supplementary list for this study was the National List of Essential Medicines for Sri Lanka [ 18].
The median number of nights to complete the study was 60 (Supplementary Table 6).
