If these two pathway subsets truly represent the interaction between chemicals and underlying molecular networks we may expect that they would be part of a super-pathway.
None of us should be thinking about how they can get it back for years; that's a super short pathway to re-damaging victims and creating new ones.
Because of its great number of nodes, this pathway was chosen by the algorithm to be particularly well drawn: all the nodes (compounds and reactions) involved in this super pathway are grouped together into a same metanode.
Metabolic profile of compounds associated to the nucleotide metabolism super pathway that varied in leaves and roots of rice plants subjected to different nitrate treatments.
In the data from BioCyc, the TCA cycle is included in the super pathway of "glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass".
Six pathways were shared between DR and Rapa + DR in the top 15 pathways: mitochondrial dysfunction, glucocorticoid receptor signaling, the super pathway of melatonin degradation, melatonin degradation I, nicotine degradation II, and serotonin degradation.
This cluster defines a KEGG super-pathway that represents a number of signalling networks directly connected to effectors functions of direct relevance with tissue morphogenesis such as Actin remodelling and Cell communication.
GeneCards is gene-centric and inherently does not present (Super) pathway-centric annotations.
When comparing the super pathways, we observed that the increase in 44 known metabolites unique to Rapa + DR mice occurred primarily in the lipid and amino acid super pathways.
Although the precise hierarchical organization of the low temperature genetic networks is yet to be defined, it appears that CBF/DREB and ZAT12 pathways (and perhaps other unidentified pathways) constitute a ' super regulon' that configure the overall low temperature stress tolerance mechanisms in Arabidopsis.
The lysine, threonine and methionine biosynthesis super-pathway of E.coli is a good example of a branched pathway that cannot be treated with two-end path finding (Fig. 2A).
