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Unfortunately they cannot be applied straightforwardly with a sufficient level of confidence to scale-up industrial units or scale-down laboratory pilots.
For metabolic time series, even fewer methods are available, and it is not often possible to state with a sufficient level of confidence and objectivity whether two time series are significantly different.
Polymerase chain reaction (PCR) primers can provide hypotheses of primary homology, as amplifications using primers target conserved flanking regions, which provide a sufficient level of confidence that the 'same' regions are being sequenced.
Despite a reasonable knowledge of the mechanisms related to proarrhythmic cardiotoxicity, there are still questions whether the new paradigm of testing will be able to provide all stakeholders with a sufficient level of confidence with the application of these novel concepts and models to drug safety.
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It is questionable if this is a sufficient level of agreement to have confidence in reports linking subjective ratings of ground hardness to injury risk and indicates that, where possible, objective measures or proven valid and reliable subjective measures should be used in future sports injury epidemiology studies.
With sufficient level of confidence for ICL as a potential drug target, GlaxoSmithKline (in collaboration with Global TB Alliance) has performed the first ever high-throughput screening (HTS) in 2000 but has terminated in 2005 after screening about 900,000 compounds as the outcome was modestly successful [ 34, 68].
Notwithstanding, we believe that sufficient level of confidence would ultimately require different types of analyses, each focusing on one or few predictions of the kind provided in thismanuscript.
We barely have a sufficient level of individual mutualised public service organisations with mature practices of governance, culture and leadership.
I've always believed that any action done with a sufficient level of consciousness and commitment is never wasted.
For now there can be no single arbiter of what constitutes a sufficient level of real impact.
Look for a sufficient level of accuracy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com