The phrase "a subtle modification in" is correct and usable in written English.
It can be used when discussing a slight change or adjustment in a particular context, such as a process, design, or system.
Example: "The researchers implemented a subtle modification in the experimental setup to improve the accuracy of the results."
Alternatives: "a slight adjustment to" or "a minor change in".
Low level fold-change acts in favor of a subtle modification of brain gene expression, much as has been suggested for task specialization [ 41].
Some roles of the Tβ4 and Tβ10 couple are linked to a subtle modification of their relative amounts [11].
Problems in the translation of the avoidance items in the PTSD instruments might be responsible for this difference, as subtle modification in the translation process may turn PTSD avoidance criteria (like "less interest in important activities" or "feeling as if future plans will not come true") into unspecific depressive items that are unrelated to a traumatic experiences.
This excellent ability to find food is certainly one of the reasons for their success in cave colonization, and probably results from several subtle modifications in their brains, governing such a complex trait.
Our findings indicate that subtle modifications in the peptide moiety of lipopeptides have a great impact on the immunomodulatory properties of these molecules.
This material opens an avenue for the preparation of new functional materials by conversion of the nitrile group into amines, carboxylic acids, amino acids and chiral groups, according to the desired application, by subtle modifications in the synthetic methodology.
Subtle modifications in the equilibrium of NP flora could lead to different etiological profiles of AOM and eventually other respiratory tract infections.
These fundamental differences in enzymatic activity do not arise from changes in the catalytic mechanism but rather are determined by subtle modifications in the primary sequence and structure of these proteins.
Subtle modifications in the structure of various GM regions in IGA subjects may contribute to the behaviors resulting from excessive online gaming, such as issues associated with impulse control, behavioral inhibition, executive functioning, attention, and general cognitive functioning.
