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The phrase "a subtle irregularity" is correct and usable in written English.
It can be used to describe a minor or slight deviation from what is expected or normal, often in contexts such as art, design, or analysis.
Example: "Upon closer inspection, the artist's work revealed a subtle irregularity that added to its charm."
Alternatives: "a slight anomaly" or "a minor deviation."
Exact(1)
Although our preliminary assessment indicated that the serum level of estrogen in SirT1ko/ko female mice was not overtly altered, it remains possible that a subtle irregularity or an individual variation of the estrogen level or ERα expression might be attributed to the reduced fertility.
Similar(59)
A 3-dimensional acquisition may also improve resolution of small or subtle irregularity of the prostate margins.
Subtle irregularity may be seen between the margin of the tumour and the junctional zone in cases of early invasion.
The notion that analysis must consist somehow in the uncovering of hidden meanings underlies also the recent tendency of some of the Oxford philosophers to take as their business an examination of the subtle irregularities of ordinary language.
The p120-catenin homozygotes are viable and fertile; p120ctn308 mutation has been reported to induce a delayed, but complete DC and subtle irregularities of the leading edge in the majority of mutant embryos [60].
However, discerning the subtle irregularities that were visible to an expert's eye proved beyond the operators' capabilities, and the developers could not write software to perform that expert task.
Mr. Poole said subtle irregularities in piloting or maintenance could, for example, burn more fuel.
Its formation probably was triggered by subtle irregularities in the big bang, adds Batuski.
Staining for calbindin, calretinin, NeuN and parvalbumin demonstrated subtle irregularities of cortical lamination with mild neuronal loss, most marked in layers II and III (Fig. 1f).
A subtle signal?
Iranians are a subtle people.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com