Bulk poly(A) tail length was not seemingly affected in the oxt6 mutant, but poly(A) site selection was different, indicating a subtle effect on polyadenylation in the mutant.
The reconfiguration takes place through a subtle effect called quantum tunneling, in which the droplet does not have enough energy to wriggle from one configuration to the other, but simply pops from one to the other as if burrowing through an energy barrier, a team of chemists reports today in Science.
So, diabetes might have a subtle effect on cognition even in the early stages of the disease.
However, we also found that mutations to both netrins and fra had a subtle effect on Integrin localisation, in that the basal gradient of βPS within PMECs was strongly reduced, and an increased signal of both βPS and αPS1 was detected at the PMEC/VM interface.
Thus, forced expression of Dlx5 in immature chondrocytes resulted in accelerated chondrocyte hypertrophy in the axial skeleton and a more subtle effect in the growth plate of limbs.
These and previous findings suggest that the mutation in COG4 generates a more subtle effect in the COG complex function, for instance by affecting recruitment of other regulatory components in membrane tethering.
But preoperative hypovitaminosis D had a subtle effect on pain intensity scores in early postoperative period.
However, we cannot rule out a more subtle effects in protein transport, such as less effective transfer of the proteins from the inner import channel.
Our ability to detect subtle effects in a dataset with a high degree of random variation is reassuring.
One such experiment, called MAQRO, hopes to test fundamental features of quantum theory and perhaps search for subtle effects in a quantum picture of gravity – something that physicists can so far see only in the haziest terms.
