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The phrase "a substantive definition of" is correct and usable in written English.
It can be used when discussing the meaning or essence of a concept, term, or idea in a detailed and meaningful way.
Example: "In this paper, we will provide a substantive definition of democracy to clarify its various interpretations."
Alternatives: "a meaningful definition of" or "a thorough definition of".
Exact(1)
But how could we arrive at a substantive definition of the threshold, and what would the implications be for treatment decisions?
Similar(59)
Additional limitations include the lack of substantive definitions of AKP and PFOA in many cases.
Not all studies adhered to a uniform definition of substantive sulfa exposure.
We prefaced the findings with a substantive overview of student engagement definitions and indicators, which revealed three types of engagement (behavioral, emotional, and cognitive) that informed how we classified articles.
Definitions like this emphasize TEK as a substantive body of knowledge that is created and stored by human societies to aid in their flourishing in the face of environmental and natural resources challenges.
"We come here today with a substantive package of changes".
"There should be a substantive understanding of the Indian scenario.
We propose a substantive model of its antecedents and consequences.
To construct a substantive theory of postpartum fatigue.
However, from a substantive point of view, the difference was rather small.
Leaving aside these issues, the Google Books corpus nevertheless provides a substantive test of our six dictionaries.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com