The phrase "a substantive concern" is correct and usable in written English.
It can be used when discussing an issue or topic that is significant or meaningful in a particular context.
Example: "The committee addressed a substantive concern regarding the environmental impact of the proposed project."
Alternatives: "a significant issue" or "a meaningful concern".
Sikkink recounts the reemergence of human rights as a substantive concern, showing how external pressures from activist groups and the institution of a human rights bureau inside the State Department have combined to remake Washington's agenda, and its image, in Latin America.
However, there is a substantive concern with respect to data presentation that needs to be addressed in a revised version.
But over time – and especially since the Tories came back with their unexpected majority – any substantive concern with sharing the pain disappeared, and we were left only with spin.
A less substantive concern is that LTP is also present in a couple of glial cells.
A more substantive concern is that oral drugs may have low and unpredictable bioavailability in contrast to the immediate and complete bioavailability after i.v. administration.
"Governor Sebelius has tangled with the White House before and will again if needed, but the response to the State of the Union message was not the time for it". A far more substantive concern with Sebelius could be that she doesn't provide what Obama truly needs.
Specific comments: A specific and substantive concern raised by both peer reviewers concerns the lack of in vivo data.
Another says: 'He should spend a long time out of the limelight.' Pirc, the corporate governance watchdog, said: 'Lying to protect one's private life is understandable, if not excusable, and not in itself a substantive governance concern for investors.
"The local GPs expressed substantive concern only about the quality of care at the trust after the announcement of the Healthcare Commission investigation, when it had become obvious there were issues and when they were specifically asked".
The substantive concern is what is the role of rotating flagella in establishment of the symbiosis?
1) The most substantive concern regarding the data is 'where is the rest of it?'.
