The phrase "a substantially more significant" is correct and usable in written English.
It can be used when comparing the importance or impact of two or more things, emphasizing that one is notably greater than the other.
Example: "The new policy will have a substantially more significant effect on employee productivity than the previous one."
Alternatives: "a considerably greater" or "a markedly more important".
So what this package does is provide an additional boost that is substantially more significant than I think most economic forecasters had expected.
The most significant p-value for both local 2D scans (QTL A: −log10(P) = 4.39; QTL C: −log10(P) = 4.44) was not substantially more significant than our most significant single QTL models (QTL A: -log10(P) = 3.19; QTL C: −log10(P) = 3.5).
Bishop and Lowell's correspondence is substantially more significant in its actual status as a correspondence between friends and literary peers than in its hypothetical status as romantic love.
Generally, sample sizes 100 and 250 and (in some instances) 500 would lead to substantially more significant results if we decided to use the quantiles of the limiting distribution rather than the bootstrap-based ones.
Therefore, before you can make significant improvement in your middle-aged marriage, you need first to respect it just as it is, the fact that it has lasted, and that it's substantially more significant than you give it credit for".
The trend seen with IP infants having higher representation of homozygosity for KIR2DL3 and C2 compared to EU infants was substantially more significant post MVL adjustment and also appears to be apparent under conditions of low maternal viral load (Table 2), again highlighting a role for KIR2DL3, in the absence of its ligand, with increased infant IP-susceptibility to HIV-1.
Removal of the phylogenetic and random background noise allows to identify substantially more significant coevolving positions in protein families and it has been shown that MIp can identify higher number of contacting residues compared to other methods of detecting coevolution [29].
