The phrase "a substantially more potent" is correct and usable in written English.
It can be used when comparing the effectiveness or strength of one substance or idea to another, indicating a significant increase in potency.
Example: "The new formula is a substantially more potent solution for treating the condition than the previous version."
Alternatives: "considerably stronger" or "significantly more effective".
While 34 is substantially more potent than cocaine as a DAT inhibitor, it is approximately four times less potent than cocaine in mimicking the discriminative stimulus properties of cocaine in rat.
This series represents a significant improvement on previous classes of compounds, being substantially more potent and largely retaining activity in the presence of serum.
Last, the new N1 C7 annulated derivatives presented herein are substantially more potent than their respective N1 C2 annulated counterparts, previously reported.
The anti-viral and anti-proliferative actions of IFN-α were substantially more potent against WISH and Daudi cells than 293 and RPMI 1788 cells, respectively.
Comparison of the cytotoxicity of KS119 in cultured cells lacking O6-alkylguanine-DNA alkyltransferase (AGT) to an agent such as Onrigin™, which through base catalyzed activation produces the same critical DNA G-C cross-link lesions by the generation of 90CE, indicates that KS119 is substantially more potent than Onrigin™ under conditions of oxygen deficiency, despite being incompletely activated.
It just so happens that the studies that have been conducted on these substances have found that they are substantially more potent than other hallucinogenic compounds, and the study's data suggest that extremely small amounts of these drugs can cause seizures, cardiac and respiratory arrest, and even death.
By contrast, ethyl acrylate and acrylic acid were substantially more potent with RD50 values of 315ppm (DeCeaurriz et al., 1981) and 685ppm (Buckley et al., 1984), respectively.
Similarly, their aminophenols were both cytotoxic and mutagenic and were substantially more potent, causing nearly 100% cell killing and significant mutagenicity at levels below 10μMM.
For example, an Fc-engineered anti-CD19 antibody, with 100- to 1000-fold increADCC Adeliveredvered substantially more potent antitumor activity than its IgG1 analogue in mouse tumor models [66].
