Sentence examples for a substantially larger study from inspiring English sources

Thus, it seems that a substantially larger study would be needed.

However, in order to evaluate clinical endpoints a substantially larger study population and longer observation period are needed.

Although we are confident that our analyses are valid within their context, is possible that these factors might be shown to be important in a substantially larger study.

Therefore, this work should be considered a pilot study, and the reliability of cerebral metabolic changes measured by MD for diagnosis or prediction of BM in patients with SAH will have to be confirmed prospectively in a substantially larger study population.

To achieve 80% power to detect a QTL accounting for 30% of the variability in phenotype approximately 800 sibling pairs would be required (a substantially larger study than any conducted to date), assuming no recombination between the QTL and the observed markers and using a significance level of 0.05 (Amos and Elston, 1989).

We now propose to conduct a multi-centre study to test these findings in a substantially larger subject group, and to determine the cost effectiveness of this treatment.

Using microarrays containing highly specific LNA probes for over 600 human miRNAs - a substantially larger number than in most previous studies - 64 miRNAs were found to be misexpressed in AML in a statistically significant manner.

Although effective risk reduction counseling and condom promotion has positive public health implications, substantially larger study sizes may be required to achieve adequate numbers of HIV endpoints in a clinical trial.

Our study, with substantially larger study samples (n with gout = 24,768 and n with HF = 3,564), was able to detect independent associations with each of these two factors.

In the final analysis, this substantially larger study included data from 4506 SNPs typed in 730 multiplex families which between them provided almost 1000 affected relative pairs.

A substantially larger recent study of 191 patients with TOF who did not have a chromosomal abnormality or recognised syndrome identified two novel TBX1 variants.