The phrase "a substantially increased number" is correct and usable in written English.
It can be used when discussing a significant rise in quantity or frequency of something.
Example: "The study revealed a substantially increased number of participants in the program compared to last year."
Alternatives: "a significantly higher number" or "a markedly increased number".
Although the liver from obese WT mice only displayed a few activated HSCs, visualized with alpha-smooth muscle actin (α-SMA) staining, the liver from obese Sesn2−/− mice contained a substantially increased number of activated HSCs (Supplementary Fig. 9f,g).
They have shown that a substantially increased number of neurons in cat areas 17 and 18 responded optimally to the exposed orientation after long-term (>45 days) GR started at P21 28.
In both populations, the WGS derived maps delimit a substantially increased number of hotspots (Additional file 1: Table S2).
Our finding that it is important to include offspring sex as factor in the analyses led to the identification of a substantially increased number of n-3 LCPUFA-responsive genes.
Without a substantially increased number of samples and non-treated human-passaged C. albicans longitudinal isolates, it is infeasible to adequately model this system for particular point mutations and genes affected.
At the beginning of the 2007 08 influenza season, however, detection of a substantially increased number of oseltamivir-resistant influenza viruses A (H1N1) (ORVs) was reported, mainly in countries in Europe where the prevalence varies, with the highest levels in Norway (67%) and France (47%) (11 – 11 ).
However, the substantially increased number of parameters for complex signaling pathways would challenge parameter estimation using psychophysical data from QST.
Substantially increased number of HKs could indicate towards efficient signal transduction capacity of the multi-trophic fungi, P. lilacinum, under rapidly changing environmental conditions.
Only the public sector, including the NHS and civil service fast stream, continued to hire in substantially increased numbers.
"It is inevitable that courts and tribunals will struggle to manage caseloads with substantially increased numbers of self-represented litigants," the CJC study notes.
To discover the answers to these questions, substantially increased numbers of patient-specific hiPSC-derived neurons must be generated.
