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The phrase "a substantially higher variability" is correct and usable in written English.
It can be used when discussing differences in data, performance, or characteristics that show a significant increase in variability compared to a baseline or another group.
Example: "The new model demonstrated a substantially higher variability in test results, indicating a need for further analysis."
Alternatives: "a significantly greater variability" or "a markedly higher variability".
Exact(1)
Given this, coverage of employed also exhibits a substantially higher variability across countries (Figs. 1 and 3).
Similar(59)
Probes within DMRs exhibited substantially higher variability in the external dataset.
Approximately two thirds of the within-community variability in NOx was explained by TRP, a substantially higher amount of variation than was explained by any other traffic metric (unpublished data).
Due to the large variability of occlusive arterial disease and outcome after surgical revascularization, possibly a substantially higher patient number is needed to measure an effect of preconditioning on clinical endpoints.
Or a substantially higher fine for littering.
You are simply getting a higher quality economy product, often for a substantially higher price.
In the event of complications from donation, women would receive a substantially higher payment than normal.
Graduates with scientific training are employed at a substantially higher rate than the national average.
Babies born at North Central Bronx also run a substantially higher risk of some serious problems.
The giant bank's prediction is for a substantially higher stock market.
That's a substantially higher percentage than the country on the whole, according to the Census Bureau.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com