The phrase "a substantially high level" is correct and usable in written English.
It can be used when describing a degree or extent of something that is significantly elevated or above average.
Example: "The project requires a substantially high level of expertise to ensure its success."
Alternatives: "a significantly elevated level" or "a considerably high level".
Enzyme preparation from the S2 cells expressing SeAPN exhibited a substantially high level of aminopeptidase activity, demonstrating its function as APN.
Research findings by Robak et al. [ 11] show that serum VEGF has a substantially high level of expression in SLE patients and is positively correlated with the ESR and SLEDAI score.
Also, in the study under discussion we detected a substantially high level of the pro-inflammatory cytokine, IL-6 in NTI patients supporting its possible role as an endocrine cytokine with a regulatory effect on many endocrine systems [ 30], including thyroid gland [ 31].
We found that when cases with clear cell RCC showed a clinical manifestation of high serum Ca, the majority of tumors expressed a substantially high level of PTHLH mRNA i.e., a PTHLH expression signal of >1.275 by our qRT-PCR assay.
Also, from a computer science perspective, it could offer a substantially higher level of control than is currently available.
It should lead to the global population stabilising, although at a substantially higher level than it is now.
A promotion is defined as advancement to a job that requires a substantially higher level of competency or substantially different responsibilities (i.e., higher market target within a broad banded structure).
Control cultures showed a substantially higher level of phosphorylation of T181, compared to the other sites tested (Figure 4), and both QA and OA resulted in a minimal increase in the phosphorylation of this site over the control level.
Importantly, these changes have been sufficient that in non-forested protected areas, although on average NDVI in surrounding areas has remained consistently higher than in the core of protected areas, in 2006 it was at a substantially higher level in the core than it was in the surroundings in 1982 (Fig. 4c).
It may reflect a reduced efficiency of energy acquisition and processing during lactation in non-capital breeders [50], [51], a failure to minimize the thermoregulatory losses of dependent offspring [52] and/or a substantially higher level of general activity due to increased sensitivity to disturbance [53].
The rationale is that if a gene in e.g. soil has a substantially higher level of orthology to proteins in sea, compared to the rest of the proteins in soil, then it is less likely to be a common fixture of soil.
