In contrast, transplant of B cells that received the identical expression cassette via nucleofection of plasmid vector substantially heightened antibody formation against FIX, a response that could be blocked by toll-like receptor 9 (TLR9) inhibition.
Recent years have seen substantially heightened interest in the discovery of tankyrase inhibitors (TNKSi) as new promising anticancer agents.
Drivers who tested positive for both alcohol and drugs were at substantially heightened risk relative to those using neither alcohol nor drugs (Odds Ratio = 23.24; 95% CI: 17.79, 30.28).
Arthur's statements suggest that in a context marked by ongoing uncertainty and fear, the semiotic potency of biomarker numbers as transparent, material indices may be substantially heightened.
In addition, there is good evidence from our work and that of others, that production of IL-10 and TGF-β is substantially heightened in H. polygyrus infection 17, 31.
Its refineries will substantially heighten Suncor's ability to process its own synthetic crude.
"That could substantially heighten trust, I would even say would bring it back," Ms. Schäfer said.
In particular, the 2009 swine-like influenza A [A(H1N1 pdm09] pandemic heightened our awareness.
It is not an exact replica, but a heightened reality.
A potential mechanism involved in a heightened response to estrogen is through SRC proteins.
