The phrase "a substantial volume in" is correct and usable in written English.
It can be used when discussing a significant amount or quantity of something, often in a specific context such as research, data, or resources.
Example: "The study revealed a substantial volume in the data collected over the past decade."
Alternatives: "a significant amount of" or "a considerable quantity of".
Our previous work [ 14], together with a substantial volume of in vitro and in vivo research from around the world, has verified the toxicity of A β [ 15, 16].
The next stage followed the 2004 revisions to the feed-in tariffs in Germany when a substantial volume of solar parks were constructed.
Still, even when studying subproteomes of plasma/serum, the potential biomarkers deriving from a local disease process such as solid cancer will be diluted in a substantial volume, which represents the sum of the cellular processes of the body.
3 A primary product was defined to be any product of farm, forest or fishery, or any mineral, in its natural form or which has undergone such processing as is customarily required to prepare it for marketing in substantial volume in international trade (as defined in Ad Article XVI of the GATT).
Traders positioning for continued bearish movement in the price of the underlying stock through the next few months are generating substantial volume in out-of-the-money put options in the March and April contracts.
This method is superior to conventional techniques because of the reduction of high-dose area of a substantial cardiac volume in those cases where the parasternal lymph nodes are part of the target volume.
This combination strongly suggesting that a lahar of substantial volume (100 m3/s) was in transit.
Whereas no significant difference in PXN-GFP intensity and MitoTracker Red intensity between stimulated and unstimulated cells was observed, there was a substantial mitochondrial volume change in response to HGF in WT, P52L, P233L, and D399N.
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The ability to collect phloem exudates, both readily and in substantial volume from white lupin, without the use of a chelating agent, provides a valuable tool for studying the macromolecular composition of such exudates in a legume.
