The phrase "a substantial variance of" is correct and usable in written English.
It can be used when discussing significant differences or changes in data, measurements, or conditions.
Example: "The study revealed a substantial variance of results between the two groups, indicating a need for further investigation."
Alternatives: "a significant difference in" or "a considerable deviation from".
There was a substantial variance in the number of clones which was not explained by age.
A substantial natural variance of the PEWY residues was revealed and phylum-specific patterns were identified.
In multi-level models that considered center as a level of analysis, substantial variance was accounted for by centers, pointing to the importance of considering center-level predictors in future research.
Our finding that cerebral volume accounts for substantial variance in a variety of measures is fully consistent with this view.
Pre-test variation accounted for a substantial amount of variance in transition ratings in addition to the post-test scores, indicating a low level of present-state bias.
Finally, although the models in the current study explained a substantial amount of variance in parents' intentions, a large proportion of variance in the target behaviours remains unexplained.
Established prenatal and birth-related variables explain a substantial amount of variance in PTSD symptoms, but the amount of explained variance can be substantially increased from 43% to a total amount of 68% when theoretically-derived cognitive variables are additionally taken into account.
Yet, while personal experience with extreme weather seems to explain very little to no variance in negative affect (R = 0.006), negative affect explains a substantial amount of variance in risk perceptions of climate change (R = 0.29).
A substantial amount of variance (26%) in infecting parasite communities was explained by variation among collection sites.
Genetic factors explained a substantial proportion of variance in EC (58%) and the outcome variables of optimism (55%), general self-esteem (45%), happiness (48%), and self-derogation (29%).
