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'a substantial value of' is correct and usable in written English.
You can use this phrase to describe a large or significant value or amount. For example: This property has a substantial value of over $1 million.
Exact(3)
In all of the presented cases, adsorbed chromate anion transfers a substantial value of electronic charge (ranging from about −0.6 to about −1.1e, see Table 1) to the adsorbents.
NRI only showed a substantial value of 18.4% for model 2 in the prediction of fatal cardiovascular events.
Surface loaded particles, IO-NB, were found to have a lower transverse (r2) relaxivity than free IO-MHPC, although still at a substantial value of 68.2 mM–1 s–1.
Similar(57)
However we have also found that we are able to price our horses above the prices asked by private individuals, horse traders, and auctions because the customer puts a substantial value on the level of comfort they gain by purchasing their horse from GFX, applying professional business practices.
The first segment has a very strong preference for the investment program having the largest total reduction in traffic deaths; the second segment assigns a substantial value to an equal distribution of reductions of traffic deaths across the Netherlands.
These arguments show clear the substantial value of achieving an adequate molecular cartography of the human MSCs.
In the presence of a tightly bound counterion (Cl−), the binding energy drops to the still substantial value of ∼20 kT.
"Therefore, we are examining how best to realise the substantial value of the Parsons Brinckerhoff business".
Last night I read this report that a small investment firm was pleading with Aol to get its act together; "The current market price of Aol fails to reflect the substantial value of the sum-of-its parts.
The importance of an asymmetric structure design to achieve substantial values of transition dipole matrix elements was revealed, and an asymmetric two-well periodic structure was proposed as a possible solution maximizing the optical matrix element of the terahertz transitions of interest.
Ethyl acetate and chloroform fractions also revealed substantial values of TFC, showing maximum amount of flavonoids.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com