The phrase "a substantial underestimation of" is correct and usable in written English.
It can be used when discussing a situation where the true value or impact of something has been significantly undervalued or miscalculated.
Example: "The report revealed a substantial underestimation of the project's costs, leading to budget overruns."
Alternatives: "a significant miscalculation of" or "a considerable undervaluation of".
However, neglecting to account for ageing error in natural mortality rate estimates resulted in a substantial underestimation of reference points.
The other explanation for the ANU's anomalous finding is what appears to be a substantial underestimation of the ~70% of national emissions outside of the power sector – the emissions from direct combustion, transport, fugitives, agriculture, industrial processes, waste, and land use and forestry (LULUCF).
This in turn may result in a substantial underestimation of the true SNP heritability.
Furthermore, additional limitations of our analysis may have caused a substantial underestimation of the cost-effectiveness of the WINGS intervention.
In the real data set we analyzed, Chao's estimate was a substantial underestimation of the true value.
Inclusion of these patients in the pre-specified efficacy analysis may have resulted in a substantial underestimation of the treatment effect.
However, even with this small value, the use of a model with no gene flow would lead to a substantial underestimation (1.5×) of the split time of the two N. anomalus lineages.
The influence of noise in the data is especially relevant for the estimates of PBF: high noise levels (i.e. low CNR values) lead to a substantial underestimation and a significant loss of accuracy in the PBF estimates.
But that may be a "substantial underestimation," the study's authors wrote, because many incidents are never made public.
Conclusions: These results suggest that uncontrolled confounding from a beneficial parameter, and imprecision of this confounder, may cause substantial underestimation of the effects of a toxic exposure.
These results suggest that uncontrolled confounding from a beneficial parameter, and imprecision of this confounder, may cause substantial underestimation of the effects of a toxic exposure.
