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The phrase "a substantial topic of" is correct and usable in written English.
It can be used when discussing a significant subject or theme within a particular context, such as an essay, article, or conversation.
Example: "Climate change is a substantial topic of discussion in today's environmental debates."
Alternatives: "a significant subject of" or "an important issue of".
Exact(1)
But Dr. Lisa Capaldini, a San Francisco primary care physician, says that anal Pap tests had nonetheless emerged in the past couple of years as a substantial topic of debate among her colleagues.
Similar(59)
Another substantial topic of the book is just how incorrect most of the information collected about us actually is.
In Art and Intention: A Philosophical Study, Paisley Livingston has performed the very valuable service of corralling a substantial number of topics regarding the intersection of art and intention between the covers of one book.
While we recognized that our AHD should not merely cover competencies that were tested in the past, and not all competencies were testable in a multiple-choice format, we discovered a substantial number of topics that were examined but never formally covered at AHD, especially in general internal medicine, infectious diseases, hematology and rheumatology.
The definition of a successful IS has become a topic of substantial research and debate [ 3- 7].
Clinical applications of muscle regeneration strategies are very limited although the topic receives a substantial amount of interest in basic science and preclinical studies (Corona and Greising 2016; Kwee and Mooney 2017).
Ray's expression of disgust and his laundry list of purportedly more substantial topics sounded not unlike some of the show's harshest critics, professional and amateur, who didn't seem to know how to react to Dunham's precisely observed, knowing depiction of intimate connections between young women.
The use of the DMT in real clinical practice setting has been a topic of substantial debate for payers at hospital and CCAA level.
Students were required to study a range of topics, including a substantial amount of British history, the school inspectors said.
54% of the GPs reported that they had made changes in their practice following the evaluation and 25% had specific plan to do so (of these 25% there was a fraction which had already made changes but still had plans regarding others topics) and a substantial part of these changes involved the whole organization.
Students will be expected to engage in research and discussion on the topic and produce a substantial body of work for presentation and final critique.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com