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The capability to deliver samples in a controlled manner across a two-dimensional hybridization detection platform represents a substantial technical challenge in the development of quantitative and reusable biochips.
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Although it does not pose any substantial technical challenge, special care would nevertheless be required as to the integrity of the data as the database will be accessed by multiple processes.
The commendable drive to reduce radiation exposure to patients has turned attention to the combination of PET with MRI, a combination that represents substantial technical challenges beyond those of PET/CT.
Though important, these findings must be viewed in the context of the substantial technical challenges associated with a screen of this breadth and depth, most notably the sensitivity of the macrophage responses to variations in the bacterial inoculum, which could not be perfectly normalized across 10,100 mutants.
Making Do Not Track technology work would involve substantial technical challenges, according to Richard M. Smith, a Boston-based Internet consultant and privacy advocate.
The measurement of scintillation light from the crystals poses substantial technical challenges.
Intel, the world's leading maker of chips, said the Chinese standard presented substantial technical challenges that would prevent it from meeting Beijing's deadline.
Due to the presence of much higher concentrations of other immunoglobulin isotypes, the assessment of specific serum IgE antibody poses substantial technical challenges.
Though the advantages are potentially huge, this hybrid fabrication approach raises substantial technical challenges to the design of vehicle structures and the associated joining processes.
But until some substantial technical challenges are overcome, you are more likely to see such displays on shelf-edges and signs than wrapped around a member of the digerati.
Work on organisms from these environments poses substantial technical challenges, making every new insight all the more exciting.
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