"a substantial subset of" is correct and commonly used in written English.
It means a large portion of a larger group. For example, "We surveyed a substantial subset of the population to get a more accurate representation of public opinion."
Overall, these data suggest that a substantial subset of the Notch-induced transcriptome requires functional HIF2α.
This suggests that currently available drugs could be used effectively in a substantial subset of patients.
The proofs of soundness and completeness over a substantial subset of our extended version of PDDL+ are presented.
Evidence is presented for a pathogenic role of the agrin/neurotrypsin system in a substantial subset of sarcopenia patients.
This indicated that in PXY-positive cells ARF5 antagonizes the effect of overall auxin signalling on a substantial subset of target genes.
A substantial subset of patients begins to experience vasoplegia earlier than previously described, both at CPB start and throughout the use of CPB.
Even when differentiation cues are blocked, premature Otx2 overexpression is sufficient to exit the naive state, induce transcription of a substantial subset of primed pluripotency-associated genes, and redirect Oct4 to previously inaccessible enhancer sites.
The principal conclusion is that rotation and lamination is capable of accessing a substantial subset of the complete properties closure when the initial polycrystal lamina possesses a strong crystallographic texture.
Some studies were never able to follow up on the final outcomes of a substantial subset of patients; others used researchers intimately involved with the development of the prognostic tool, and not impartial observers, to validate findings.
While the scale of President Obama's immigration policy is large relative to previous exercises of executive discretion over immigration policy, it is far from the only area where the executive branch has chosen to systematically ignore a substantial subset of lawbreakers.
Although it has been shown that, in the worst case, there is no parallel algorithm for unification that is faster than the best sequential algorithm, we show that there is a substantial subset of unifications that may be speeded up by being performed in parallel.
