Sentence examples for a substantial shutdown from inspiring English sources
The immediate response of a cell on imposition of a detrimental stress is to take evasive action, which is exhibited by a substantial shutdown of transcription.
In 32D-V559D cells, imatinib, flumatinib, and sunitinib treatment all effectively abolished the phosphorylation of KIT, ERK1/2, and STAT3 (Fig. 2), showing substantial shutdown of the KIT and downstream signaling pathways.
Politically, Republicans are reeling, bearing a substantial amount of the blame for the government shutdown and stalemate.
His office estimates that 275 direct jobs will be lost from the planned shutdown of two local plants, a substantial loss for Burney, with its population of just over 3,000 people, and similarly sized nearby towns.
A substantial and powerful portion of the conservative electorate are pretty happy about this; the applause John Boehner received from his colleagues at the word "shutdown" made that pretty clear.
A substantial and satisfying volume.
This is a substantial upgrade".
We made a substantial bid.
A substantial irony enters here.
That is a substantial amount.
This is a substantial grievance.
