That is a substantial shift in British politics and a healthy one.
Over the past two decades, there has been a substantial shift in the global innovation landscape.
This suggests that MPB-disturbed forests are undergoing a substantial shift in landscape-level species composition.
Some health care advocates in the city applauded what they saw as a substantial shift in the mayor's position.
We may be on the cusp of a substantial shift in broadband policy away from Washington towards decisionmakers in communities across the country.
There has also been a substantial shift in the age/employment of volunteers in the last several years, I assume due to economic forces.
The results of two new studies may signal a substantial shift in the way psychiatrists and researchers think about treatment for severely depressed patients.
It describes a substantial shift in the racial and ethnic makeup of farmworkers in the Hudson Valley since the 1980s, from mostly black to predominantly Hispanic.
The loss of Glenn, who has five interceptions, could cause a substantial shift in the N.F.L.'s third-ranked pass defense.
However, the Pentagon's budget for next year is up by 5percentnt, indicating a substantial shift in resources to the military.
In contrast, the top-down cascade observed in this study is unique because it appears to drive a substantial shift in the benthic-pelagic coupling.
