Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
a substantial separation
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "a substantial separation" is correct and usable in written English.
It can be used to describe a significant distance or division between two entities, whether physical, emotional, or conceptual. Example: "The study revealed a substantial separation between the two groups in terms of their opinions on the matter."
✓ Grammatically correct
Science
News & Media
Formal & Business
Encyclopedias
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
4 human-written examples
As a consequence of its supervised nature, LDA was able to provide a substantial separation of the BJT into clusters, corresponding to each transistor array.
A substantial separation between strong and weak weights occurred, and either state was preserved indefinitely during ongoing activity.
Science
After the successful completion of a 1-year feasibility phase, during which a substantial separation of HbA1c levels between the intensive therapy (INT) ("experimental") and CON ("standard") groups was achieved (9), an additional eight centers were added, and full-scale recruitment began.
Science
To have a substantial separation between groups with regard to HbA1c values, excellent glycemic control was arbitrarily defined as an average HbA1c <6.5% in the past 12 months and fair/poor control as an average HbA1c ≥8.5% in the past 12 months.
Science
Human-verified similar examples from authoritative sources
Similar Expressions
55 human-written examples
Master soil horizon was the most significant predictor of the distribution of cations within the soil profile with substantial separation between A horizon samples and B and C horizon samples.
Science
Capillary electrophoresis (CE) is a separation technique that benefits from, e.g., substantial separation efficiency, fast analysis, and relatively low operation cost.
However, the substantial separation of some boards may also imply independent solutions to some problems, as is the case, for example, with the unique "rocker" shape associated with the Z-Flex Rocker board.
As can be seen in figure 2A there is substantial separation of mitochondrial (red) and non-mitochondrial (green) diseases using this approach.
Science
Strengths of the DCCT/EDIC include its randomized, controlled design with substantial separation in HbA1c achieved by treatment assignment; the detailed longitudinal characterization of diabetes complications; and the unusually long duration of follow-up, particularly for a clinical trial.
Science
A second striking feature occurs in Figure 1c and d, where the Kaplan-Meier curves for OS in E1690 are practically in complete overlap for the two treatment arms, while in Figure 1c, there is substantial separation between the two treatment arms in the E1684 study.
There was substantial separation in the average locations of the two lowest response categories (0 = never and 1 = some of the time) and between the second and third (2 = most of the time and 3 = all of the time) response categories.
Science
Expert writing Tips
Best practice
When using "a substantial separation", ensure the context clearly defines what is being separated and the criteria that make the separation significant. For instance, quantify the separation with data or specific metrics whenever possible.
Common error
Avoid using "a substantial separation" if the difference or division is marginal or insignificant. Using weaker terms like "a slight difference" or "a minor gap" maintains credibility.
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "a substantial separation" functions as a noun phrase that describes a significant division or gap between two or more entities. Ludwig examples show its usage in various scientific and analytical contexts, like separating groups based on HbA1c levels or BJT clusters.
Frequent in
Science
75%
News & Media
12%
Formal & Business
6%
Less common in
Encyclopedias
6%
Wiki
0%
Reference
0%
Ludwig's WRAP-UP
The phrase "a substantial separation" is a noun phrase used to describe a significant division or gap. Ludwig's analysis shows the phrase is grammatically correct and suitable for formal and scientific contexts, although it appears in other contexts as well. The AI confirms that the phrase indicates an important distinction. When using the phrase, ensure that the context clearly defines what is being separated and the magnitude of the difference is genuinely significant. Alternatives include "significant division", "considerable gap", and "marked distinction" for different shades of meaning.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
significant division
Focuses on the act of dividing something significantly, rather than the state of being separated.
considerable gap
Emphasizes the space or difference between two points or states.
marked distinction
Highlights a clear and noticeable difference between two things.
pronounced difference
Stresses the obviousness and ease of noticing the dissimilarity.
notable divergence
Indicates a significant deviation or departure from a common point.
clear demarcation
Implies a well-defined boundary or distinction between two entities.
distinct cleavage
Suggests a sharp and decisive split or division.
wide chasm
Emphasizes the large and potentially unbridgeable gap between two things.
serious rift
Describes a significant disagreement or break in a relationship.
major schism
Indicates a fundamental division, often within a group or organization.
FAQs
How can I use "a substantial separation" in a sentence?
You can use "a substantial separation" to describe a significant gap or division between two things. For example, "There was a substantial separation between the experimental group and the control group in terms of test scores."
What can I say instead of "a substantial separation"?
You can use alternatives like "significant division", "considerable gap", or "marked distinction" depending on the specific nuance you want to convey.
Is it more appropriate to say "a substantial separation" or "a significant separation"?
Both "a substantial separation" and "a significant separation" are grammatically correct and convey a similar meaning. The choice between them depends on personal preference and the specific context, though substantial might imply a greater degree of separation.
What is the difference between "a substantial separation" and "a slight separation"?
"A substantial separation" indicates a large and important difference or division, whereas "a slight separation" suggests a minor or insignificant difference. The choice depends on the magnitude of the actual separation you are describing.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested