The phrase "a substantial route of" is correct and usable in written English.
It can be used when discussing a significant or important path, method, or means of achieving something.
Example: "The research identified a substantial route of funding that could support the new initiative."
Alternatives: "a significant pathway of" or "a major avenue of".
(Sidenote: since eBay will still be working with PayPal on a non-exclusive basis, a report this week alleged that eBay stands to gain a share in Adyen of up to five percent if chooses to route a substantial portion of its transactions through the Dutch company. There is nothing about this arrangement in the Adyen's prospectus).
The new route opened in 1906, and a substantial part of the GCR's traffic to and from London was diverted onto the Alternative Route, damaging the profitability of the MR's railway operations.
For a substantial amount of time (epochs), topology discovery and route creation operations are not repeated [1]. 3.
Unlike Kostina's assumptions [ 25], we propose an evolutionary scenario in favour of two diffusion routes in southern Europe and North Africa as revealed by a substantial proportion of shared alleles that were specifically detected along each of the two diffusion routes.
In total, Figure 2 covers the migration routes from 36 brigades and a substantial number of private reindeer units, giving a total of over 1,000 households of nomadic reindeer herders in the Yamal peninsula.
The A7 motorway runs through hills, rugged coastal terrain, and urban areas, requiring a substantial number of bridges, viaducts, and tunnels along the route.
As the A7 motorway route runs through rugged terrain, it utilizes a substantial number of major structures bridges, viaducts, tunnels, underpasses, flyovers, and culverts.
However, a substantial portion of BBS observers conducted surveys on >1 BBS route, causing the grouping factor of observer to lose the nesting property.
A substantial proportion of cancer patients are diagnosed through an emergency route (hereafter described as emergency presentation) (Elliss-Brookes et al, 2012; Gunnarsson et al, 2013).
Conclusion: A substantial dose of topotecan can be delivered by the IP route, achieving cytotoxic plasma levels of topotecan, with acceptable toxicity.
