The phrase "a substantial role of" is correct and usable in written English.
It can be used when discussing the importance or significance of a particular factor, element, or individual in a specific context.
Example: "The research highlighted the substantial role of community engagement in improving public health outcomes."
Alternatives: "a significant role in" or "an important part of".
He has never performed a substantial role of any sort in a staged production, although he has sung Papageno in concert.
This pattern implies a substantial role of inter-state mobility in the first years following the shock.
The reduction in affiliative behavior seen with increased activity at 5-HT1A receptors indicates a substantial role of serotonin activity in the expression of social behavior.
The behaviour of the surface concentrations of the components of solution in the region of the anodic overpotential points to a substantial role of electromigration processes that can be played by them in copper passivation in sulphate solutions.
These authors thereby attribute a substantial role of asymptomatic individuals on the importation of infection.
This provides strong support for a substantial role of the extracellular domain in MUC1-mediated resistance to anoikis.
This presents the first experimental evidence of a substantial role for the formation of vibrationally excited final states in the total process of hydrogen evolution.
Nevertheless, these genes do play a substantial role for phylogenies of for instance parasitic plants [e.g. [ 13, 15]] where plastid genomes can be highly modified [ 16, 17].
The delay of the development of the exocrine pancreas in HEP fish does not play a substantial role in downregulation of the zymogens that were investigated here.
Pork appears to play a substantial role as a part of the diet for most respondents in the four countries of this study.
2. The issue of reduction has played a substantial role in both philosophy of mind and philosophy of social science.
