Sentence examples for a substantial response in from inspiring English sources

We observed in a series of patients that treatment with the BRAF inhibitor vemurafenib yielded a substantial response in extracerebral metastases, but brain metastases developed.

The purpose of these surrounding flankers and the task was to ensure that the target discrimination required focused spatial attention, and that the target ensemble should drive a substantial response in the early visual cortex including retinotopic areas (see Noesselt et al., 2002).

Whereas ET-1 drives a substantial response in the global transcriptome, a large proportion of which requires ERK1/2 signaling [ 21], insulin had a relatively minor effect on global RNA expression, suggesting that PI3K signaling through PKB/Akt does not substantially affect transcription even though PKB/Akt phosphorylates, for example, Forkhead transcription factors that are then inactivated [ 17].

Later Thursday, Trump gave a more substantial response in a six-minute address to the country in which he declared, "It is not enough to simply take actions that make us feel like we are making a difference, we must actually make that difference".

For instance, a recent study on steelhead demonstrates that only one generation in captivity can result in a substantial response to selection on traits that are beneficial in captivity but maladaptive in the wild (Christie et al. 2012).

Mr. Levy said he expected to see a substantial response from the F.B.I. in the coming days.

Mr. Pan's lawyer, Irwin Rochman, said, "We will have a substantial response to the indictment in the near future".

Cluster 3, including 18 % of females and 24%% of males, displayed a substantial response with a large variation in cortisol values between baseline and peak (178 mmol/L, 183 mmol/L).

In the × dimension (phosphoproteins), the data indicated that the change by time point tended to cause the most substantial response in phosphoprotein levels.

All estrogens, both physiologic and nonphysiologic, caused substantial responses in all three types of Ca response measurements, as we have observed previously [ 15].

Furthermore, significant differences were observed for the supplementary motor area (BA 6), which similarly resulted from a substantial negative response in the blocked design in response to erotic – neutral stimuli.