Sentence examples for a substantial refinement from inspiring English sources

Size exclusion chromatography afforded a facile approach to quantify the mass of the unattached polymer, and provide a substantial refinement to estimates of chain graft density beyond traditionally-used approaches, such as thermogravimetry.

Application of the conditional Granger analysis resulted in a substantial refinement of the plasticity pattern provided by PGC.

In particular, among imaging modalities, whole-body computed tomography (CT) represents a substantial refinement in the diagnostic work-up of multitrauma patients [ 6].

In this article, we report a substantial refinement to the DArT genotyping technique which allowed its implementation for the yellow fever mosquito Aedes aegypti.

Mapping of ESTs to an existing genome sequence by spliced alignment has allowed substantial refinement of gene models in a number of eukaryotic organisms (e.g. [ 17, 18]).

It was deduced that the observed increase in conductivity was caused by a substantial morphology refinement and increased degree of cocontinuity after copolymer addition leading to the formation of double percolated networks in the blends.

The negotiations commonly involved an iterative sequence of discussion and deal changes, frequently involving substantial refinement of the nature of the potential deal as discussions within the acquiring firm proceeded.

Substantial refinement of the item set was required to establish a consistent model, and a second sample (n = 883) was surveyed to replicate the model.

Because the diagnosis of concussions has undergone substantial refinement since the 1960s and 1970s, when many of the survey respondents had played, a modern description of symptoms -- such as nausea or seeing stars following a strong blow to the head, not simply being knocked unconscious -- was provided.

However, the current consensus (e.g. Fortnow 2009) is that these approaches are still in need of substantial refinement or that genuinely new methods will be required in order to yield the desired separations.

These results indicate that the simple epidemic detection techniques recommended to date require substantial refinement before they can be considered operationally robust, since they lack the required sensitivity in detecting aberrant case burdens.