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Testing the safety of vaccines and other biologically active drugs now accounts for a substantial proportion of tests, especially where monkeys are concerned.Still, the medical definition conceals at least some cosmetic use, particularly of the botulinum toxin, which is used to treat eye disease but more commonly to smooth out wrinkles.
Furthermore, a substantial proportion of tests (19%) had distributions significantly more skewed than expected under neutrality.
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Although the impact of rapid diagnostic tests on prescriber behaviour in settings where diagnosis is currently syndromic (based on symptoms) is encouraging, for malaria a substantial proportion of negative tests by any technique are still ignored.
Remarkably, 36 (42%) of samples tested were PCR positive, suggesting excretion of a CoV by a substantial proportion of ferrets tested.
Our testing indicates that our gene prioritization method is capable of meaningful candidate gene prioritization and performs strongly in a substantial proportion of cases tested.
In all cases, a substantial proportion of the tested TAL1 OSs was active, ranging from 47% to 100% (Additional file 1: Table S17).
The occurrence of both positive and inverse seroconversions up to the age of 24 years implies that β-cell autoimmunity represents a dynamic process, and that it can be induced at any age in childhood and adolescence and may be transient in a substantial proportion of subjects testing positive for a single antibody.
Although Grainge et al (2005) found a significantly higher HPV positivity among cases compared to controls, a substantial proportion of women tested negative for HPVs in baseline smears less than 4 years (67%), and 4 13 years (74%), before the diagnosis of CIN3/cervical cancer.
Although the sensitivity of Xpert MTB/RIF test is higher than microscopy, a substantial proportion of children with negative test had positive MTB cultures.
Screening female survivors of pediatric Hodgkin Lymphoma for breast cancer with MRI and mammography detected tumors at an earlier stage than prior studies of mammography alone, although a substantial proportion of women required additional tests for benign imaging findings.
This approach to treatment of locally advanced pancreatic cancer is safe and promising, with good local control for a substantial proportion of patients, and merits testing in a randomised trial.
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