The phrase "a substantial progress in" is not correct.
It should be "substantial progress in" without the article "a." You can use it when discussing significant advancements or improvements in a particular area or field.
Example: "The team has made substantial progress in developing the new software."
Alternatives: "significant progress in" or "considerable advancement in".
Eradicating such invasive head restraint from otherwise non-invasive monkey studies could represent a substantial progress in terms of Reduction and Refinement.
Due to the internal impetus and external pressure on China to strengthen protection for technology, China has made a giant stride and made a substantial progress in legislation, enforcement and other areas.
Although hydraulic fracturing is a mature technology that has been used commercially since the late 1940s, the development of unconventional hydrocarbon fields with the combination of directional drilling and multistage hydraulic fracturing in the last two decades gave rise to a substantial progress in both operations and associated modeling.
In recent years, the need of particle-physics collider and neutrino experiments to cover very large detection areas (thousands of square meters) has driven a substantial progress in the development of detectors technologically more advanced, cheaper and simpler to handle.
These findings imply that, if the occupational mismatch results from a combination of immigrants' poor (or nonequivalence of) foreign education quality, language proficiency, and literacy skills, without a substantial progress in these specific human capital characteristics, the isolated effects of relative improvements in occupational match will not be rewarding for immigrants.
With this work, we can make a substantial progress in future medicine.
A substantial progress has been made in development and management of water resources in the last 50 years.
Recently, Sri Lanka has achieved a significant reduction in malaria incidence since 2000 and embarked on a malaria elimination phase in 2009 of a substantial progress toward elimination of malaria in the last decade [ 8].
Over the last decades, a substantial progress has been achieved in defining different patterns of tumor microcirculation.
But make no mistake: If the Senate passes this bill, after the partisan noise has died down, we will look at the 2010s as a period of substantial progress in American health care.
According to a joint report, substantial progress in fighting sickness and death from infectious diseases is possible over the next decade with drugs, vaccines, and other strategies that are already available.
