Sentence examples for a substantial problem and from inspiring English sources
Fraud is a substantial problem, and the attitude toward it has changed little over the years, other editors say.
Neurological complications of paediatric cancer are a substantial problem and are associated with significant morbidity and loss of quality of life for long-term survivors of paediatric cancer.
In order to preserve the Kansas law, he will have to show that noncitizen voter registration is a substantial problem and that nothing short of the state's proof-of-citizenship law can stop it.
Kobach, who was also on the voter fraud commission with von Spakovsky, has to show that noncitizens getting on the voter rolls is a substantial problem and that nothing short of asking people to provide proof of citizenship can prevent it.
However, resistance remains a substantial problem and is the focus for the development of new therapeutic strategies targeting putative resistance mechanisms.
In a region in which land subsidence is already a substantial problem and past events are less and less predictive of future hydrological behavior, inadequate technical knowledge and information exchange can result in maladaptive investments: infrastructure that may actually increase risks from future flooding (see Eakin and Appendini 2008).
Corneal endothelial dysfunction is a substantial problem in FECD, and it is accompanied by visual disturbance which provides a major indication for corneal transplantation surgery [138].
In this article we demonstrate how this is a substantial problem in practice and present a method that greatly helps ameliorate the problem.
Long-term sick leave due to common mental health problems e.g. adjustment disorders, clinical burnout/exhaustion, anxiety and depression is a substantial problem in many countries, and a major reason for this is thought to be psychosocial stress [ 1, 2].
In one in four cases there was a "clinically important delay" before the patient was seen by a consultant, access to CT and MRI scanning is a "substantial problem" at many hospitals and in one in five hospitals "do not attempt resuscitation" orders were signed by "very junior trainee doctors".
Racial disparities in the management and outcomes of chronic diseases, such as diabetes, remain a substantial problem for the quality and equity of health care nationally.
