The phrase "a substantial point of" is correct and usable in written English.
It can be used when discussing an important or significant aspect of a topic or argument.
Example: "In our discussion, we must address a substantial point of concern regarding the project's budget."
Alternatives: "a significant aspect of" or "an important element of".
JH I have a substantial point of disagreement with both you and Zeke here.
The point of confluence of the two diagrams of u and u′ indicates a substantial point of variation and the existence of the trend.
These present results allow to determine the optimal sample size required to detect a model deviation considered relevant from a substantial point of view with given risks of an error of the first and the second kind.
It will be overpowered if samples are large, hence irrelevant model deviations will become significant, although they might be acceptable from a substantial point of view, which, in turn, might give rise to generally scorn the LRT as such.
From a substantial point of view, several politically sensitive questions have not been solved.
We must state that the results, despite being numerically different, were similar from a substantial point of view.
And "Presumptive," like most political novels, requires a substantial point-of-view character who's willing to make an offer of his soul.
We think that it is a substantial point to ensure the performance of metallic contacts before any measurements.
The Spanish prime minister Jose Zapatero says: "We have not let a single substantial point of the constitutional treaty go".
The "narrow" interpretation of the Regulation of Investigatory Powers Act 2000, that it was not a crime to eavesdrop messages already listened to by their intended recipient, "was misleading not on a minor point, but on the most substantial point of all".
Our findings point to a substantial degree of concordance between the opinions of two parties and suggest that the physician and patient share the same opinion on the patient's work ability.
