The phrase "a substantial overlap of" is correct and usable in written English.
It can be used when discussing similarities or shared elements between two or more subjects, such as ideas, data sets, or groups.
Example: "There is a substantial overlap of interests between the two research teams, which could lead to collaborative opportunities."
Alternatives: "a significant intersection of" or "a considerable similarity in".
Although mean values were often significantly different between fibrous and lipid-rich coronary arterial plaques, a substantial overlap of CT numbers was found, precluding a reliable characterisation and differentiation of the various non-calcified coronary arterial plaques [15].
To identify commonly demethylated CGs we grouped AZA and DAC replicates, respectively, and found a substantial overlap of CGs that were demethylated by both drugs (Figure 2D).
The extent of overlap between D1 and D2 receptors in another brain region, the striatum, is still not completely resolved [30], although recent work has shown that there is a substantial overlap of expression in medium spiny neurons [31].
However, supervised analysis of genes with a tendency to differential expression between Mdr2-KO and Mdr2-KO/HCV-Tg samples revealed a substantial overlap of pathways affected by the HCV transgene and the Mdr2-KO mutation (Table S2).
In contrast to the above mentioned differential effects of AZA and DAC on cell viability and gene expression, our data demonstrate a substantial overlap of genes demethylated by both drugs.
Interestingly, the cytoskeleton and Metal Ion/Cation binding categories represented a significant number of the differentially expressed genes, with a substantial overlap of genes categorized in both of these ontology categories.
On the other hand, there is a substantial overlapping of sarcoidosis and control group results, therefore it is impossible to set up a clear cut-off level for "abnormal" results.
25 However, there was a substantial overlap for all of the biomarkers tested between the patients and controls.
Notwithstanding important differences, there is a substantial overlap between many of these conceptions of the good as witnessed by the commending of the Golden Rule ("Do unto others as you would have them do unto you") in many religions.
The guts of different individuals have a substantial overlap in terms of species composition and function because it was always thought that human gut flora was very variable".
Several studies reported that although there is a substantial overlap, the pattern of organ involvement is peculiar, with higher frequencies of lung, lymph nodes, and peripheral nervous system involvement.
