DCT → PMX sequence reduced the IC50 under the level of simultaneous exposure in Capan-1 and MIA PaCa2 lines, while it did not induce any substantial modification in CFPAC-1 line.
RS-guided chemotherapy decision-making resulted in a substantial modification of adjuvant chemotherapy usage in node-negative and node-positive ER+ EBC.
In this paper a substantial modification of the model is proposed in order to enhance its capability in predicting the residual strength kinetics with emphasis to the "sudden drop" of strength before catastrophic failure.
So, based on our results, a substantial modification of corneal biomechanics occurs only in the very first follow-up time after SMILE (7 days).
In summary, the presence of MyoVIIa, Atoh1, Pou4f3, Sox2, Nhlh1, Nhlh2 and Fgf8 expression in cells near intraganglionic vesicles inside the remaining ganglia implied a substantial modification of the cellular identity of these cells in Neurod1 CKO mice.
Similar to what has been obtained in the ammonia concentration variation, a substantial modification on the quasi-NRs morphology was obtained when the zinc salt concentration was altered.
Our experimental observations require a substantial modification of the model of interaction between benzene molecules and graphite surfaces: in contrast to recent studies we find only weak kinetic surface friction, but a substantial dissipative interaction during inter-molecular collisions.
Hence, in order to avoid a significant desorption of both Sb and N as well as a substantial modification of the InAs QDs, we studied the effect of the CL growth temperature in a range between 450°C and 480°C.
In addition, the proposed system is a low-cost solution because there is no need for a substantial modification of the LTE-A system architecture.
As seen, such changes of Na − Nd and τn lead to a substantial modification of the spectrum.
