The phrase "a substantial margin the" is not correct and usable in written English.
It appears to be an incomplete phrase and lacks clarity without additional context.
Example: "The candidate won the election by a substantial margin."
Alternatives: "a significant margin" or "a considerable margin."
Sedna is, by a substantial margin, the most distant object yet seen in the solar system.
"I felt then, and nothing in the intervening 16 months has changed by mind, that difficult as the task is, the Fed was by a substantial margin the institution best positioned to effectively supervise the integration of capital markets and traditional financial intermediation," Mr. Tarullo said.
At this point he had already lost at the polls by a substantial margin, the election having taken place on the 27 October.
Notably, the box C/D scaRNAs 2 and 9 were, by a substantial margin, the most abundant non-coding RNAs recovered in the coilin immunocomplexes.
By a substantial margin the items with the three highest factor loadings on the Alternative subscale (Emo 0.80; Punk, 0.81; and Gothic, 0.80) were those used to construct our categorical measure of Alternative identity.
"By a substantial margin, this is the highest transfer fee paid for an M.L.S. player and represents the recognition we have gotten in every quarter of the soccer world.
Banda was defeated by Bakili Muluzi of the UDF by a substantial margin, and the UDF won a majority of seats in the National Assembly.
If he is perceived as winning the debate, and the jobs number misses by a substantial margin to the upside (meaning that more than about 180,000 jobs are created), Mr. Romney's position could become extremely desperate.
Lord Rose, the former Marks & Spencer chief executive who chairs Britain Stronger in Europe, insisted last week that his side will win the referendum "by a substantial margin" despite the gloomy poll predictions.
In late February 1845, the House by a substantial margin and the Senate by a bare 27 25 majority approved a joint resolution offering terms of annexation to Texas.
The bus structure reinforced by the composite roll bar was able to secure a substantial margin of the survival zone as well as to meet the requirement specified by ECE R66.
