The phrase "a substantial induction of" is correct and usable in written English.
It can be used in contexts where you are discussing a significant increase or introduction of something, often in scientific or formal writing.
Example: "The study revealed a substantial induction of immune response following the vaccination."
Alternatives: "a significant increase in" or "a considerable introduction of".
Another study using nrd::lac fusions on multicopy plasmids and hydroxyurea exposure in wildtype indicated a substantial induction of beta-galactosidase after treatment which was substantially LexA-independent [36].
In principle, a substantial induction of OPC differentiation could be unfavourable, if it occurs at the expense of OPC numbers.
Corroborating this, we measured a substantial induction of CS expression and mtDNA copy number during differentiation of both white and brown adipocytes, with induction being particularly pronounced during brown adipogenesis (Fig. 1B).
Cells adapting to ethanol as carbon source showed a substantial induction of catalase activity (Fig. 1A).
In the presence of IL-1β, there was a substantial induction of MMP-1 (5.3-fold), comparable to that seen in the presence of keratinocyte-conditioned medium.
Knockdown of p53 resulted in the significant repression of miR-509-5p miR-509-5p miR-509-5p overexpressinn of p53 resulthe in a substantial inducells of miR-509-5p expression in all cell lines.
On the other hand, there was no indication of any substantial induction of anoikis-resistant potential by Twist1 overexpression using PLC/PRF/5 and HuH7 (data not shown).
In wild-type plants, exposure to 200 ppm MMS led to a substantial induction after 1 d of all marker genes examined, with the exception of AtCYCD1 1, which was induced after 2 d.
Yet the pattern and levels of CYP1A1 expression in Arctic animals indicate a substantial induction in those beluga.
In contrast to the MET3 gene, which showed no significant change in expression in any environmental condition tested, the MET6 gene showed a substantial induction in response to methionine and a dramatic transcriptional induction in response to homocysteine.
MoMDC which have been activated by TLR7 and/or 8 agonists show substantial induction of a large number of cytokines (Table 3).
