Sentence examples for a substantial increased risk from inspiring English sources

The present study highlights that common variants of inflammatory cytokine genes exert a modest effect on risk of DN and a combination of risk alleles confer a substantial increased risk of nephropathy in type 2 diabetes among Asian Indians.

Subjects with all three factors had a substantial increased risk of developing CWP.

However, a substantial increased risk associated with acculturation remained after adjustment for these variables, although it was not statistically significant.

Observational data do not support the concern that there is a substantial increased risk of mortality due to the use of digoxin in women.

In our study, obese women had a substantial increased risk of GDM (OR 4.14; CI 95%: 3.81-4.50) compared to normal weight women.

Besides this classical specificity, the first question regards anogenital human papillomavirus (HPV) infections, which are associated with a substantial increased risk of developing cervical and anogenital cancers [ 5].

Janov et al did not find any substantial increased risk of LBW and no congenital abnormalities among newborns of 15 women with prepregnancy Hodgkin's disease compared with the general population (Table 3).

11 12 15 27 The observed increased prevalence of overall major birth defects in association with exposure to SSRIs was lower than the 21-30% increased risk reported in previous Danish studies, 11 12 27 but extends the findings from a previous Finnish study reporting no substantial increased risk of overall birth defects.

We found no substantial increased risk for breast cancer with increasing the number of siblings.

In addition, studies conducted in relation to ovarian cancer provide evidence against substantial increased risk associated with mEH polymorphisms [ 33].

Women with BRCA1/ BRCA2 mutations are at substantial increased risk for metachronous contralateral breast cancer throughout the follow-up period.