Sentence examples for a substantial increase in expression of from inspiring English sources

As shown by RT-qPCR, there is a substantial increase in expression of Snail and Zeb-1 and decrease in epithelial marker E-cadherin (Fig.  5A-C).

In several brain regions, formation of β-amyloid plaques triggers reactive astrogliosis characterised by a substantial increase in expression of GFAP, increase in astroglial cytoskeleton, and overall hypertrophy of astrocytes.

As early as 4 h and 8 h after inhibitor removal there was a substantial increase in expression for two ligands of EGFR, namely amphiregulin and epiregulin.

These findings agree with the expression data, in that both activators are required for a substantial increase in expression upon derepression (Table 1).

Notably, sustained stimulation by VEGF-loaded PLLA mat resulted in a substantial increase in the expression of proangiogenic mRNAs of CSCs in vitro.

A substantial increase in the expression of Grp94, and to a lesser extent Grp78, was observed in lactic acid-treated compared to control SH-SY5Y cells (Fig. 5A).

In this study we also detected a substantial increase in the expression of this gene upon LPS challenge.

However, on re-oxygenation there was a substantial increase in the expression of these p53-regulated apoptotic genes.

The phenotypic and genotypic changes that occur in response to SFRP1 loss are consistent with EMT, including a substantial increase in the expression of ZEB2.

qRT-PCR revealed a substantial increase in the expression of TBX18, WT1 and TCF21 in RA-treated LM cells compared with other signalling conditions (Fig. 2A).

In contrast, there was a substantial increase in the expression of MIP-2 (CXCL2) mRNA and IL-1β mRNA following LPS treatment compared to control.