The phrase "a substantial in" is not correct and usable in written English as it is incomplete and lacks context.
It may be intended to describe something significant related to a noun that follows, but it needs additional words to form a complete thought.
Example: "There is a substantial increase in productivity this quarter."
Alternatives: "a significant amount in" or "a considerable change in".
To gain permission to live and work in the UK, a person usually has to be one of exceptional talent, looking to make a substantial (in excess of £1m) investment in the UK or only looking for temporary work.
This inconsistency between the systems implies that the causes of underprediction have a substantial in vitro component as opposed to possible extrapolation methodological bias, as discussed above.
A substantial in depth characterization of both peptide preparation protocol and Aβ membrane permeation has previously been carried out using calcein release, TEM, circular dichroism, SPFS, and atomic force microscopy [15], [27].
In this study, we have demonstrated a substantial in vivo treatment effect, which can be induced by the application of sodium butyrate or the orally applicable tributyrin in human prostate cancer.
More recently, a substantial in vitro study of the reductive activities of BciAs from maize and cucumber, as well as those from rice and A. thaliana, on the 8V forms of Chl a, Chlide a, Pchlide, magnesium protoporphyrin monomethyl ester and magnesium protoporphyrin IX, revealed that the rice and maize enzymes could reduce all of the tested substrates.
In the first quarter they and Ginnie Mae (which unlike Fannie and Freddie has always enjoyed the explicit backing of the state) guaranteed 96.5% of all newly originated mortgages, according to Inside Mortgage Finance, a newsletter.It is almost certain that the companies will no longer be allowed to hold a substantial in-house portfolio of securities.
The results presented appear to suggest that an approximately linear relationship exists between a load-frequency parameter and the central deflection of the plates considered, for a substantial in-plane loading range.
Finite-element modeling was conducted to show that a substantial in-plane stress gradient through the film thickness exists during the development of cracks, and that this gradient likely affects the saturation crack spacing.
At the time of study the facility housed an OPD, IPD, MCH, TB and HIV department and a substantial in-house laboratory.
Intracranial injury was the most common reason for ICU admission in both adult and overall populations and carried a substantial in-ICU mortality, similar to findings in previous studies in other developing countries [ 30, 37, 38].
… the shortest delay in supply results in a substantial drop in the number of customers.
